Stock Ticker

The antirheumatic drug sulfasalazine ameliorates acute renal failure (ARF) induced by polymyxin B

  • Falagas ME, Kasiakou SK. Colistin: the revival of polymyxins for the management of multidrug-resistant gram-negative bacterial infections. Clin Infect Dis. 2005;40:1333–41.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Magiorakos AP, Srinivasan A, Carey RB, Carmeli Y, Falagas ME, Giske CG, et al. Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance. Clin Microbiol Infect. 2012;18:268–81.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Davis SD, Iannetta A, Wedgwood RJ. Activity of colistin against Pseudomonas aeruginosa: inhibition by calcium. J Infect Dis. 1971;124:610–2.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Gupta S, Govil D, Kakar PN, Prakash O, Arora D, Das S, et al. Colistin and polymyxin B: a re-emergence. Indian J Crit Care Med. 2009;13:49–53.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Kallel H, Hamida CB, Ksibi H, Bahloul M, Hergafi L, Chaari A, et al. Suspected acute interstitial nephritis induced by colistin. J Nephrol. 2005;18:323–6.

    PubMed 

    Google Scholar
     

  • Avedissian SN, Liu J, Rhodes NJ, Lee A, Pais GM, Hauser AR, et al. A Review of the Clinical Pharmacokinetics of Polymyxin B. Antibiotics (Basel). 2019;8:31.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Yokosawa T, Yamada M, Noguchi T, Suzuki S, Hirata Y, Matsuzawa A. Pro-caspase-3 protects cells from polymyxin B-induced cytotoxicity by preventing ROS accumulation. J Antibiot (Tokyo). 2019;72:848–52.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Kagi T, Naganuma R, Inoue A, Noguchi T, Hamano S, Sekiguchi Y, et al. The polypeptide antibiotic polymyxin B acts as a pro-inflammatory irritant by preferentially targeting macrophages. J Antibiot (Tokyo). 2022;75:29–39.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Kagi T, Inoue A, Noguchi T, Suzuki W, Takano S, Otani K, et al. The NLRP3 Inflammasome Is a Major Cause of Acute Renal Failure Induced by Polypeptide Antibiotics. J Immunol. 2024;212:1807–18.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Jo EK, Kim JK, Shin DM, Sasakawa C. Molecular mechanisms regulating NLRP3 inflammasome activation. Cell Mol Immunol. 2016;13:148–59.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Huang Z, Yu M, Tong S, Jia K, Liu R, Wang H, et al. Tissue-specific expression of the NOD-like receptor protein 3 in BALB/c mice. J Vet Sci. 2014;15:173–7.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Tsai PY, Ka SM, Chang JM, Chen HC, Shui HA, Li CY, et al. Epigallocatechin-3-gallate prevents lupus nephritis development in mice via enhancing the Nrf2 antioxidant pathway and inhibiting NLRP3 inflammasome activation. Free Radic Biol Med. 2011;51:744–54.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Mantovani A, Dinarello CA, Molgora M, Garlanda C. Interleukin-1 and Related Cytokines in the Regulation of Inflammation and Immunity. Immunity. 2019;50:778–95.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Noguchi T, Sekiguchi Y, Kudoh Y, Naganuma R, Kagi T, Nishidate A, et al. Gefitinib initiates sterile inflammation by promoting IL-1beta and HMGB1 release via two distinct mechanisms. Cell Death Dis. 2021;12:49.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Sekiguchi Y, Takano S, Noguchi T, Kagi T, Komatsu R, Tan M, et al. The NLRP3 Inflammasome Works as a Sensor for Detecting Hypoactivity of the Mitochondrial Src Family Kinases. J Immunol. 2023;210:795–806.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Kagi T, Noguchi T, Matsuzawa A. Mechanisms of gefitinib-induced interstitial pneumonitis: why and how the TKI perturbs innate immune systems?. Oncotarget. 2021;12:1321–2.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Kagi T, Tan M, Suzuki W, Otani K, Suzuki S, Hirata Y, et al. Benzalkonium chloride initiates proinflammatory responses via NLRP3 inflammasome activation. J Toxicol Sci. 2025;50:11–21.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Kim HY, Choi YJ, Kim SK, Kim H, Jun DW, Yoon K, et al. Auranofin prevents liver fibrosis by system Xc-mediated inhibition of NLRP3 inflammasome. Commun Biol. 2021;4:824.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Gan HT, Chen YQ, Ouyang Q. Sulfasalazine inhibits activation of nuclear factor-κB in patients with ulcerative colitis. J Gastroen Hepatol. 2005;20:1016–24.

    Article 
    CAS 

    Google Scholar
     

  • Liu X, Zhang Y, Zhuang L, Olszewski K, Gan B. NADPH debt drives redox bankruptcy: SLC7A11/xCT-mediated cystine uptake as a double-edged sword in cellular redox regulation. Genes Dis. 2021;8:731–45.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Source link

    Get RawNews Daily

    Stay informed with our RawNews daily newsletter email

    Liverpool defender left out of World Cup squad

    Madonna Covering Rent For Musicians Working At Her Old NYC Rehearsal Space

    Up 16.5%! Here’s why Hollywood Bowl stock smashed the FTSE 250 today

    Trump says Iran would not get sanctions relief in exchange for giving up enriched uranium