Stock Ticker

Factorial vignettes describe suspected early onset sepsis practice variation in a multicenter NICU antibiotic stewardship collaborative

  • Flannery DD, Ross RK, Mukhopadhyay S, Tribble AC, Puopolo KM, Gerber JS. Temporal trends and center variation in early antibiotic use among premature infants. JAMA Netw Open. 2018;1:e180164–e180164.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Oliver EA, Reagan PB, Slaughter JL, Buhimschi CS, Buhimschi IA. Patterns of empiric antibiotic administration for presumed early-onset neonatal sepsis in neonatal intensive care units in the United States. Am J Perinatol. 2017;34:640–7.

    PubMed 

    Google Scholar
     

  • Schulman J, Dimand RJ, Lee HC, Duenas GV, Bennett MV, Gould JB. Neonatal intensive care unit antibiotic use. Pediatrics. 2015;135:826–33.

    Article 
    PubMed 

    Google Scholar
     

  • Stiemsma LT, Michels KB. The role of the microbiome in the developmental origins of health and disease. Pediatrics. 2018;141.

  • Alm B, Erdes L, Möllborg P, Pettersson R, Norvenius SG, Aberg N, et al. Neonatal antibiotic treatment is a risk factor for early wheezing. Pediatrics. 2008;121:697–702.

    Article 
    PubMed 

    Google Scholar
     

  • Alm B, Goksör E, Pettersson R, Möllborg P, Erdes L, Loid P, et al. Antibiotics in the first week of life is a risk factor for allergic rhinitis at school age. Pediatr Allergy Immunol. 2014;25:468–72.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Li DK, Chen H, Ferber J, Odouli R. Infection and antibiotic use in infancy and risk of childhood obesity: a longitudinal birth cohort study. Lancet Diabetes Endocrinol. 2017;5:18–25.

    Article 
    PubMed 

    Google Scholar
     

  • Saari A, Virta LJ, Sankilampi U, Dunkel L, Saxen H. Antibiotic exposure in infancy and risk of being overweight in the first 24 months of life. Pediatrics. 2015;135:617–26.

    Article 
    PubMed 

    Google Scholar
     

  • Hannan KE, Juhl AL, Hwang SS. Impact of NICU admission on Colorado-born late preterm infants: breastfeeding initiation, continuation and in-hospital breastfeeding practices. J Perinatol. 2018;38:557–66.

    Article 
    PubMed 

    Google Scholar
     

  • Hynan MT, Mounts KO, Vanderbilt DL. Screening parents of high-risk infants for emotional distress: rationale and recommendations. J Perinatol. 2013;33:748–53.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Sekar KC. Iatrogenic complications in the neonatal intensive care unit. J Perinatol. 2010;30:S51–56.

    Article 
    PubMed 

    Google Scholar
     

  • Phibbs CS, Schmitt SK, Cooper M, Gould JB, Lee HC, Profit J, et al. Birth hospitalization costs and days of care for mothers and neonates in California, 2009-2011. J Pediatr. 2019;204:118–125.e14.

    Article 
    PubMed 

    Google Scholar
     

  • Puopolo KM, Lynfield R, Cummings JJ. Committee on fetus and newborn, committee on infectious diseases. Management of infants at risk for group B streptococcal disease. Pediatrics. 2019;144:e20191881.

    Article 
    PubMed 

    Google Scholar
     

  • Nanduri SA, Petit S, Smelser C, Apostol M, Alden NB, Harrison LH, et al. Epidemiology of invasive early-onset and late-onset group B streptococcal disease in the United States, 2006 to 2015: multistate laboratory and population-based surveillance. JAMA Pediatr. 2019;173:224.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Schrag SJ, Farley MM, Petit S, Reingold A, Weston EJ, Pondo T, et al. Epidemiology of invasive early-onset neonatal sepsis, 2005 to 2014. PEDIATRICS. 2016;138:e20162013–e20162013.

    Article 
    PubMed 

    Google Scholar
     

  • Puopolo KM, Benitz WE, Zaoutis TE. AAP committee on fetus and newborn, AAP committee on fetus and newborn. management of neonates born at ≤34 6/7 weeks’ gestation with suspected or proven early-onset bacterial sepsis. Pediatrics. 2018;142:e20182896.

    Article 
    PubMed 

    Google Scholar
     

  • Puopolo KM, Benitz WE, Zaoutis TE. AAP Committee on Fetus and Newborn, AAP Committee on Infectious Disease. Management of neonates born at ≥35 0/7 weeks’ gestation with suspected or proven early-enset bacterial sepsis. Pediatrics. 2018;142:e20182894.

    Article 
    PubMed 

    Google Scholar
     

  • Ho T, Buus-Frank ME, Edwards EM, Morrow KA, Ferrelli K, Srinivasan A, et al. Adherence of newborn-specific antibiotic stewardship programs to CDC recommendations. Pediatrics. 2018;142:e20174322.

    Article 
    PubMed 

    Google Scholar
     

  • Vidavalur R, Hussain N. Interstate practice variation and factors associated with antibiotic use for suspected neonatal sepsis in the United States. Am J Perinatol. 2024;41:e1689–e1697.

    Article 
    PubMed 

    Google Scholar
     

  • Balakrishnan M, Raghavan A, Suresh GK. Eliminating undesirable variation in neonatal practice. Balancing Standardization Customization Clin Perinatol 2017;44:529–40.

    PubMed 

    Google Scholar
     

  • Alexander CS, Becker HJ. The use of vignettes in survey research. Public Opin Q. 1978;42:93–104.

    Article 

    Google Scholar
     

  • Converse L, Barrett K, Rich E, Reschovsky J. Methods of Observing Variations in Physicians’ Decisions: The Opportunities of Clinical Vignettes. J Gen Intern Med. 2015; 3:S586–94.

  • Peabody JW, Luck J, Glassman P, Jain S, Hansen J, Spell M, et al. Measuring the quality of physician practice by using clinical vignettes: a prospective validation study. Ann Intern Med. 2004;141:771–80.

    Article 
    PubMed 

    Google Scholar
     

  • Payton KSE, Wirtschafter D, Bennett MV, Benitz WE, Lee HC, Kristensen-Cabrera A, et al. Vignettes identify variation in antibiotic use for suspected early onset sepsis. Hosp Pediatr. 2021;11:770–4.

    Article 
    PubMed 

    Google Scholar
     

  • Healy H, Whitesel E, Mao W, Day CL, Murphy TG, Song CH, et al. Measuring practice preference variation for quality improvement in neonatal respiratory care. J Perinatol. 2024;44:1001–8.

    Article 
    PubMed 

    Google Scholar
     

  • Patel S, Landers T, Larson E, Zaoutis T, Delamora P, Paul DA, et al. Clinical vignettes provide an understanding of antibiotic prescribing practices in neonatal intensive care units. Infect Control Hosp Epidemiol. 2011;32:597–602.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Whitesel E, Healy H, Mao W, Pursley DM, Zupancic J, Gupta M. Measuring practice preference variation for quality improvement: development of the Neonatology Survey of Interdisciplinary Groups in Healthcare Tool (NSIGHT). BMJ Open Qual. 2023;12:e002422.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Lefrak L, Schaffer KE, Bohnert J, Mendel P, Payton KSE, Lee HC, et al. Blood culture procedures and practices in the neonatal intensive care unit: A survey of a large multicenter collaborative in California. Infect Control Hosp Epidemiol. 2023;44:1576–81.

    Article 
    PubMed 

    Google Scholar
     

  • Qureshi N, Kroger J, Zangwill KM, Joshi NS, Payton K, Mendel P. Changes in perceptions of antibiotic stewardship among neonatal intensive care unit providers over the course of a learning collaborative: a prospective, multisite, mixed-methods evaluation. J Perinatol. 2024;44:62–70.

    Article 
    PubMed 

    Google Scholar
     

  • Payton KSE, Bennett MV, Schulman J, Benitz WE, Stellwagen L, Darmstadt GL, et al. 28 NICUs participating in a quality improvement collaborative targeting early-onset sepsis antibiotic use. J Perinatol. 2024;44:1061–8.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Payton KSE, Gould JB. Vignette Research Methodology: An Essential Tool for Quality Improvement Collaboratives. Healthcare (Basel). 2022;11:7.

    Article 
    PubMed 

    Google Scholar
     

  • Conducting Cognitive Testing for Health Care Quality Reports. Content last reviewed September 2019. Agency for Healthcare Research and Quality, Rockville, MD. https://www.ahrq.gov/talkingquality/resources/cognitive/index.html.

  • Kader GD, Perry M Variability for Categorical Variables. J Stat Educ. 2007;15. https://doi.org/10.1080/10691898.2007.11889465.

  • Bapat R, Pearlman S. The role of QI collaboratives in neonatology. J Perinatol. 2025;45:417–25.

  • Dhudasia MB, Benitz WE, Flannery DD, Christ L, Rub D, Remaschi G et al. Diagnostic performance and patient outcomes with c-reactive protein use in early-onset sepsis evaluations. J Ped. 2022. https://doi.org/10.1016/j.jpeds.2022.12.007.

  • Newman TB, Puopolo KM, Wi S, Draper D, Escobar GJ. Interpreting complete blood counts soon after birth in newborns at risk for sepsis. Pediatrics. 2010;126:903–9.

    Article 
    PubMed 

    Google Scholar
     

  • Hornik CP, Benjamin DK, Becker KC, Benjamin DK, Li J, Clark RH, et al. Use of the complete blood cell count in early-onset neonatal sepsis. Pediatr Infect Dis J. 2012;31:799–802.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Benitz WE. Adjunct laboratory tests in the diagnosis of early-onset neonatal sepsis. Clin Perinatol. 2010;37:421–38.

    Article 
    PubMed 

    Google Scholar
     

  • Benitz WE, Wynn JL, Polin RA. Reappraisal of guidelines for management of neonates with suspected early-onset sepsis. J Pediatr. 2015;166:1070–4.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Cantey JB, Baird SD. Ending the Culture of Culture-Negative Sepsis in the Neonatal ICU. Pediatrics. 2017;140:e20170044.

  • Cantey JB, Prusakov P. A proposed framework for the clinical management of neonatal “culture-negative” sepsis. J Pediatr. 2022;244:203–11.

    Article 
    PubMed 

    Google Scholar
     

  • Source link

    Get RawNews Daily

    Stay informed with our RawNews daily newsletter email

    Porter Hodge, Jordan Wicks Likely To Begin Season On Cubs’ IL

    When is FA Cup quarter final draw? Date, time, TV, online live stream, ball numbers and schedule for 2025/26 last eight

    James Van Der Beek’s Daughter Emilia Remembers Late Actor On His Birthday

    Recap of non-farm payrolls: -92K and revisions make it worse