Tong, S. Y. C., Davis, J. S., Eichenberger, E., Holland, T. L. & Fowler, V. G. Staphylococcus aureus infections: Epidemiology, pathophysiology, clinical manifestations, and management. Clin. Microbiol. Rev. 28, 603–661 (2015).
Bai, A. D. et al. Staphylococcus aureus bacteraemia mortality: A systematic review and meta-analysis. Clin. Microbiol. Infect. 28, 1076–1084 (2022).
Kirby, W. M. M. Extraction of a highly potent penicillin inactivator from penicillin resistant staphylococci. Science 99, 452–453 (1944).
Lowy, F. D. Antimicrobial resistance: The example of Staphylococcus aureus. J. Clin. Invest. 111, 1265–1273 (2003).
Paul, M. et al. Are all beta-lactams similarly effective in the treatment of methicillin-sensitive Staphylococcus aureus bacteraemia?. Clin. Microbiol. Infect. 17, 1581–1586 (2011).
Cheng, M. P., René, P., Cheng, A. P. & Lee, T. C. Back to the future: Penicillin-susceptible staphylococcus aureus. Am. J. Med. 129, 1331–1333 (2016).
Resman, F., Thegerström, J., Månsson, F., Ahl, J. & Tham, J. The prevalence, population structure and screening test specificity of penicillin-susceptible staphylococcus aureus bacteremia isolates in Malmö. Sweden. J. Infect. 73, 129–135 (2016).
Richter, S. S. et al. Detection and prevalence of penicillin-susceptible staphylococcus aureus in the united states in 2013. J. Clin. Microbiol. 54, 812–814 (2016).
Chabot, M. R., Stefan, M. S., Friderici, J., Schimmel, J. & Larioza, J. Reappearance and treatment of penicillin-susceptible Staphylococcus aureus in a tertiary medical centre. J. Antimicrob. Chemother. 70, 3353–3356. https://doi.org/10.1093/jac/dkv270 (2015).
Jin, Y. et al. Genomic epidemiology and characterisation of penicillin-sensitive staphylococcus aureus isolates from invasive bloodstream infections in China: An increasing prevalence and higher diversity in genetic typing be revealed. Emerg. Microbes Infect. 11, 326–336 (2022).
Butler-Laporte, G., Lee, T. C. & Cheng, M. P. Increasing rates of penicillin sensitivity in staphylococcus aureus. Antimicrob. Agents Chemother. 62, e00680-e718 (2018).
Hagstrand Aldman, M., Kavyani, R., Kahn, F. & Påhlman, L. I. Treatment outcome with penicillin G or cloxacillin in penicillin-susceptible Staphylococcus aureus bacteraemia: A retrospective cohort study. Int. J. Antimicrob. Agents 59, 106567 (2022).
Papanicolas, L. E., Bell, J. M. & Bastian, I. Performance of phenotypic tests for detection of penicillinase in staphylococcus aureus isolates from australia. J. Clin. Microbiol. 52, 1136–1138 (2014).
Pereira, L. A., Harnett, G. B., Hodge, M. M., Cattell, J. A. & Speers, D. J. Real-time pcr assay for detection of blaz genes in staphylococcus aureus clinical isolates. J. Clin. Microbiol. 52, 1259–1261 (2014).
Kaase, M. et al. Comparison of phenotypic methods for penicillinase detection in staphylococcus aureus. Clin. Microbiol. Infect. 14, 614–616 (2008).
El Feghaly, R. E., Stamm, J. E., Fritz, S. A. & Burnham, C. A. D. Presence of the blaZ beta-lactamase gene in isolates of Staphylococcus aureus that appear penicillin susceptible by conventional phenotypic methods. Diagn. Microbiol. Infect. Dis. 74, 388–393 (2012).
Shah, M. D., Wardlow, L. C., Stevenson, K. B., Coe, K. E. & Reed, E. E. Clinical outcomes with penicillin versus alternative β-lactams in the treatment of penicillin-susceptible staphylococcus aureus bacteremia. Pharmacotherapy 38, 769–775 (2018).
Nissen, J. L. et al. Effectiveness of penicillin, dicloxacillin and cefuroxime for penicillin-susceptible Staphylococcus aureus bacteraemia: A retrospective, propensity-score-adjusted case–control and cohort analysis. J. Antimicrob. Chemother. 68, 1894–1900 (2013).
Moriyama, Y., Ishikane, M., Mezaki, K. & Ohmagari, N. Comparison of penicillins (Penicillin g and ampicillin) and cefazolin as a definitive therapy against penicillin-susceptible staphylococcus aureus (Pssa) bacteremia in Japan: A retrospective cohort study. J. Infect. Chemother. 26, 358–362 (2020).
Reynolds, G., Crawford, S., Cuenca, J., Ghosh, N. & Newton, P. Penicillin versus anti-staphylococcal beta-lactams for penicillin-susceptible staphylococcus aureus blood stream infections: A retrospective cohort study. Eur. J. Clin. Microbiol. Infect. Dis. 41, 147–151 (2022).
Mok, H. T. et al. Treatment outcomes with benzylpenicillin and non-benzylpenicillin antibiotics, and the performance of the penicillin zone-edge test versus molecular detection of blaZ in penicillin-susceptible Staphylococcus aureus (Pssa) bacteraemia. J. Antimicrob. Chemother. 78, 2515–2523 (2023).
Henderson, A. et al. Benzylpenicillin versus flucloxacillin for penicillin-susceptible staphylococcus aureus bloodstream infections from a large retrospective cohort study. Int. J. Antimicrob. Agents 54, 491–495. https://doi.org/10.1016/j.ijantimicag.2019.05.020 (2019).
Aldhaeefi, M., Pearson, J., Kanjilal, S. & Dionne, B. Penicillin versus cefazolin or anti-staphylococcal penicillins for penicillin-susceptible staphylococcus aureus bacteremia. Open Forum Infect. Dis. 7, S149 (2020).
Charlson, M. E., Pompei, P., Ales, K. L. & MacKenzie, C. R. A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation. J. Chronic Dis. 40, 373–383 (1987).
Chow, J. W. & Yu, V. L. Combination antibiotic therapy versus monotherapy for gram-negative bacteraemia: A commentary. Int. J. Antimicrob. Agents. 11, 7–12 (1999).
Dagan, R. Evidence to support the rationale that bacterial eradication in respiratory tract infection is an important aim of antimicrobial therapy. J. Antimicrob. Chemother. 47, 129–140 (2001).
Rao, S. N. et al. Treatment outcomes with cefazolin versus oxacillin for deep-seated methicillin-susceptible staphylococcus aureus bloodstream infections. Antimicrob. Agents Chemother. 59, 5232–5238 (2015).
Renaud, C. J., Lin, X., Subramanian, S. & Fisher, D. A. High-dose cefazolin on consecutive hemodialysis in anuric patients with Staphylococcal bacteremia. Hemodial. Int. 15, 63–68 (2011).
Lee, S. et al. Is cefazolin inferior to nafcillin for treatment of methicillin-susceptible staphylococcus aureus bacteremia?. Antimicrob. Agents Chemother. 55, 5122–5126 (2011).
van Hal, S. J. et al. Predictors of mortality in staphylococcus aureus bacteremia. Clin. Microbiol. Rev. 25, 362–386 (2012).
Nambiar, K. et al. Survival following staphylococcus aureus bloodstream infection: A prospective multinational cohort study assessing the impact of place of care. J. Infect. 77, 516–525 (2018).
Roth, J. A., Tschudin-Sutter, S., Dangel, M., Frei, R. & Battegay, M. Value of the pitt bacteraemia score to predict short-term mortality in Staphylococcus aureus bloodstream infection: A validation study. Swiss Med. Weekly 147, w14482 (2017).
Forsblom, E., Ruotsalainen, E., Ollgren, J. & Järvinen, A. Telephone consultation cannot replace bedside infectious disease consultation in the management of staphylococcus aureus bacteremia. Clin. Infect. Dis. 56, 527–535 (2013).
Papadimitriou-Olivgeris, M., Caruana, G., Senn, L. & Guery, B. Predictors of mortality of staphylococcus aureus bacteremia among patients hospitalized in a Swiss University Hospital and the role of early source control; A retrospective cohort study. Eur. J. Clin. Microbiol. Infect. Dis. 42, 347–357 (2023).
Lewis, J. S. Performance Standards for Antimicrobial Susceptibility Testing. 34th ed. Clinical and Laboratory Standards Institute (2024).
