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Repurposing caspofungin as a small-molecule inhibitor of Clostridium perfringens α-toxin for treatment of gas gangrene

Repurposing caspofungin as a small-molecule inhibitor of Clostridium perfringens α-toxin for treatment of gas gangrene

Mice Specific pathogen-free female C57BL/6J mice were purchased from Japan SLC, Inc. (Shizuoka, Japan) and housed under clean conditions with free access to food and water. Female mice were used to avoid unintended infections caused by male aggression and to prevent potential effects on survival outcomes, thereby ensuring reliable and consistent experimental results. Animals purchased […]

Mortgage rates fall to 6.3%: Freddie Mac

Mortgage rates fall to 6.3%: Freddie Mac

 Financial influencer Taylor Price joins ‘Varney & Co.’ to break down how shifting your mindset can help Americans grow wealth and achieve the American Dream. Mortgage rates fell this week, mortgage buyer Freddie Mac said Thursday. Freddie Mac’s latest Primary Mortgage Market Survey, released Thursday, showed the average rate on the benchmark 30-year fixed mortgage […]

Lena Dunham Spills on Snorting Lactose Lines for Wild ‘Girls’ Scene

Lena Dunham Spills on Snorting Lactose Lines for Wild ‘Girls’ Scene

Lena Dunham ‘Girls’ Scene Skimmed The Line With Fake Coke Published April 16, 2026 9:09 AM PDT Play video content Las Culturistas with Matt Rogers and Bowen Yang Lactose lines and zero regrets — that’s how Lena Dunham is spilling the tea on one of the most chaotic “Girls” scenes. Dunham shared the behind-the-scenes chaos […]

Why I think the HSBC share price could hit 2,000p by December

Why I think the HSBC share price could hit 2,000p by December

Image source: Getty Images The HSBC (LSE:HSBA) share price has been rocketing higher over the past year. It’s up 75% over this period, and trades at 1,340p. If it keeps up this pace of growth, it could hit 2,000p by the end of the year, a further 50% higher than today. Even though some might […]

Lionel Messi buys Spanish club located just outside Barcelona

Lionel Messi buys Spanish club located just outside Barcelona

Lionel Messi has taken another step into football ownership by buying UE Cornella, according to the lower league Spanish club. The Catalan outfit released a statement this afternoon claiming Messi is now the main stakeholder of the team based in Baix Lobregat, just outside Barcelona. It read: “UE Cornellà announces that Argentinian footballer and eight-time […]

Bryan Cranston Takes Shot at Shia LaBeouf in Frankie Muniz Interview

Bryan Cranston Takes Shot at Shia LaBeouf in Frankie Muniz Interview

Bryan Cranston Flips Interview Into Shia LaBeouf Roast Published April 16, 2026 8:48 AM PDT Bryan Cranston dug up some holes … and buried Shia LaBeouf in the process. The brutal moment happened during his Esquire sit-down with ‘Malcolm in the Middle’ costar Frankie Muniz … when Muniz got candid about a major career fork […]

£15,000 invested in UK shares a decade ago is now worth…

£15,000 invested in UK shares a decade ago is now worth…

Image source: Getty Images Is it worth investing in UK shares? Past performance is not necessarily a guide to what may happen in future. But it can still provide an interesting perspective on how UK shares have fared over time. The FTSE 100 has been doing well Take the flagship FTSE 100 index of leading […]

Trump announces Isreal and Lebanon ceasefire

Trump announces Isreal and Lebanon ceasefire

This isn’t a big surprise given the leaks all week but it’s still progress and a great signal that the US and Iran are on track: I just had excellent conversations with the Highly Respected President Joseph Aoun, of Lebanon, and Prime Minister Bibi Netanyahu, of Israel. These two Leaders have agreed that in order […]

Mets Trade Richard Lovelady To Nationals

Mets Trade Richard Lovelady To Nationals

The Nationals announced Thursday that they’ve acquired left-hander Richard Lovelady from the Mets in exchange for cash. Fellow southpaw Ken Waldichuk, who was recently recommended for Tommy John surgery, moves to the 60-day IL to open a spot on the 40-man roster. The Mets designated Lovelady for assignment over the weekend. Lovelady was with the […]