Mechanism of co-transcriptional cap snatching by influenza polymerase
Cloning and purification of proteins To generate H7N9 FluPol with impaired endonuclease activity, the PA(E119D) mutation was introduced into the PA gene. A pFastBac Dual vector encoding the influenza polymerase heterotrimer subunits of A/Zhejiang/DTID-ZJU01/2013 (H7N9)35, was used as a template for PCR site-directed mutagenesis and Gibson cloning. This method was also used to generate mutated […]
Texas Latinos turned out in massive numbers for Democrats
Latino voters flocked to Tuesday’s Democratic primary in Texas in droves, reversing a long-running erosion for the party ahead of this year’s pivotal midterms. The numbers were dramatic: In five different rural majority-Latino counties, more votes were cast in Tuesday’s Democratic primary than for Kamala Harris in the 2024 presidential election. “These very Hispanic counties […]
Harry Styles Says Grief Over Liam Payne Felt Co-Opted by Public
Harry Styles I Didn’t Feel Like I Owned All My Payne Grief Published March 4, 2026 11:56 AM PST Play video content Apple Music Harry Styles says it seemed like other people felt entitled to his grief after Liam Payne died … because a public expression of his feelings was expected from him. The singer-songwriter […]
US February ADP employment +63K vs +50K expected
Prior was +22K (revised to +11K) Goods +16K versus +1K last month Service +47K versus +21K last month Small business +60K vs 0K prior Medium businesses -7K vs +41K last month Large businesses +10K vs -18K last month Wages for job stayers 4.5% vs 4.5% last month Wages for job changers 6.3% vs 6.4% last […]
Poll: Will Kevin McGonigle Break Camp With The Tigers?
All around the league this spring, teams are giving their top prospects opportunities to impress this spring. In many cases around the game this year, teams have left a wide open path for their top prospects to make a run at a roster spot with minimal established competition standing in their way. That’s true of […]
Premier League text updates, goals and stats
Manchester United’s resurgence will be put to the test at Newcastle on Wednesday. The arrival of Michael Carrick has transformed United’s fortunes, taking 19 points from a possible 21 across the interim head coach’s seven games to surge up the Premier League table. They start in third with a place in next season’s Champions League […]
'Substantial reason to believe' Tony Gonzales had sex with his staffer, House probe finds
Congressional investigators have found “a substantial reason to believe” that Rep. Tony Gonzales had a sexual relationship with a subordinate — an apparent violation of House rules. POLITICO exclusively reviewed the report made by the nonpartisan Office of Congressional Conduct and delivered Wednesday to the House Ethics Committee, which has separately announced it is investigating […]
Whoopi Goldberg, Elisabeth Hasselbeck Argue Over ICE, Masks on ‘The View’
Elisabeth Hasselbeck To Whoopi You Don’t Like ICE Masks?!? Dems Are Party of Masks!!! Published March 4, 2026 11:11 AM PST Play video content ABC Elisabeth Hasselbeck had quite the comeback for Whoopi Goldberg after Whoopi said she had a problem with immigration agents hiding their faces … telling Whoopi her own political party is […]
NZDUSD higher on the day and testing topside resistance targets
The NZD/USD is trending higher today, but the recovery is now facing its most significant test of the week. The pair is currently squeezing into a dense pocket of overhead resistance that will determine if this move has “legs” or if it is simply a dead-cat bounce. The Topside Hurdle: 0.5927 – 0.5940 The Kiwi […]
Maury Povich’s Daughter Amy & Her Husband Sell Beverly Hills Home for $17.35M
Maury Povich’s Daughter Scores $17.35M in Sale of Beverly Hills Home Published March 4, 2026 11:23 AM PST Good news for Maury Povich’s daughter — she’s officially offloaded her stunning Beverly Hills pad for a cool $17.35 million. Real estate sources tell TMZ the seller is Amy Povich and her husband, Dr. David Agus … […]
