DNA repair enzyme Polβ shields developing brain from harmful mutations, study reveals

Polβ-dependent DNA demethylation is essential for neuronal development. During neuronal development, DNA demethylation at enhancer regions is required to activate gene expression. In the absence of DNA polymerase β (Polβ), indel mutations near CpG sites increase approximately ninefold, highlighting the critical role of Polβ in maintaining genome integrity during epigenetic reprogramming. Credit: Proceedings of the […]
‘Don’t check my blood pressure’

Real Madrid manager Xabi Alonso has suggested Lamine Yamal is not good for his nerves and said Real Madrid’s game against Osasuna on Tuesday should have been postponed. The Spanish FA turned down Madrid’s request to put the match back because of a lack of recovery time following the end of their Club World Cup […]
The Health Benefits of Dates and How to Enjoy Them, According to Dietitians

Sweet, chewy, and surprisingly nutritious—dates are much more than a natural candy. These little dried fruits are quickly becoming popular as both a snack and an ingredient. They’re packed with fiber, essential minerals, and antioxidants (1, 2). Plus, they make a great natural sweetener. Are all the benefits of dates too good to be true? […]
Seismology offers slab window insights

Credit: Geophysical Research Letters (2025). DOI: 10.1029/2025GL115019 Off the southern coast of Chile, three tectonic plates meet at a point known as the Chile Triple Junction. Two are oceanic plates, the Nazca and the Antarctic, which are separating in an active spreading center, creating a mid-ocean ridge between them. At the same time, both plates—spreading […]
300,000-Year-Old Skull Shows Neanderthals May Have Lived Alongside Homo Heidelbergensis

A nearly complete human skull that was discovered in a Greek cave in 1960 has remained at the center of a major anthropological debate for over six decades. However, researchers have finally settled the matter by revealing that the cranium belongs to a species that’s more primitive than both Homo sapiens and Neanderthals, yet existed […]
Ben Stiller Surprises Audience as Derek Zoolander at Film Screening

Ben Stiller They’re The Same Face!!! Surprises Crowd as Derek Zoolander Published August 18, 2025 6:26 AM PDT Ben Stiller is bringing “Blue Steel” back … surprising a packed crowd of “Zoolander” fans as his infamous character. It all went down Saturday night in Los Angeles, during a special screening of the 2001 cult classic […]
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Trump on Truth Social: We will see return of remaining hostages once Hamas is destroyed

Meanwhile, back to the other war with Ukraine and Russia, Trump posts: A big day at the White House. We have never had so many European leaders here at one time. A great honor for America!!! Let’s see what results will be??? Pres DJT. OK. Ego booster for the Pres. Those who will be in […]
Kratom faces increasing scrutiny from states and the feds

For years, state lawmakers have taken the lead on regulating kratom—the controversial herbal supplement used for pain relief, anxiety and opioid withdrawal symptoms. Some states have banned it entirely. Others have passed laws requiring age limits, labeling and lab testing. At least half of the states and the District of Columbia have enacted some form […]
Ravens Worked Out Former Bears Defender

The Baltimore Ravens are slated to be one of the best teams in the AFC again in 2025. Lamar Jackson is coming off one of his best statistical seasons, and while the Ravens still couldn’t make it to the Super Bowl last year, they played well against top-tier opponents. Their roster was strong in […]