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Early-life serological profiles and the development of natural protective humoral immunity to Streptococcus pyogenes in a high-burden setting

Early-life serological profiles and the development of natural protective humoral immunity to Streptococcus pyogenes in a high-burden setting

Study participants and sampling Mother–child pairs during the first year of life Mother–child pairs from an urban clinic, The Gambia, participating in a trial of maternal immunization with MenAfriVAC were included (NCT03746665). All samples were obtained from consenting mother–child pairs where the mother had been vaccinated with meningococcal serogroup A conjugate vaccine between 28 weeksʼ and […]

Vaping cannabinoid mixtures produces a chemical that destroys human tissue, research reveals

Vaping cannabinoid mixtures produces a chemical that destroys human tissue, research reveals

Graphical abstract. Credit: Chemical Research in Toxicology (2025). DOI: 10.1021/acs.chemrestox.4c00448 In addition to being used recreationally, marijuana and cannabidiol, or CBD, one of the cannabinoids produced by the marijuana plant, are thought to have medical benefits, such as helping with chemotherapy-induced nausea, treating epilepsy, relieving pain and helping with a variety of mental health issues. […]

‘We won’t fear the Championship’

‘We won’t fear the Championship’

Wrexham manager Phil Parkinson says his side will not fear the Championship when they return to the second tier for the first time in 43 years on Saturday. The Hollywood story since actors Rob McElhenney and Ryan Reynolds took over in 2020 has seen the club promoted from the National League to the Championship in […]

Democrats make a Trump-inspired U-turn on redistricting

Democrats make a Trump-inspired U-turn on redistricting

The last time House Democrats held the majority, they made a sweeping package of good-government reforms — including an attempt to end partisan gerrymandering — a centerpiece of their legislative agenda. “The people should choose their politicians,” then-Speaker Nancy Pelosi said in 2021, moments before the House passed the bill that would later die in […]

Shawn Mendes’ Shirtless Shots To Kick Off The Singer’s 27th Bday!

Shawn Mendes’ Shirtless Shots To Kick Off The Singer’s 27th Bday!

Shawn Mendes’ Shirtless Shots … Happy 27th Bday!!! Published August 8, 2025 12:01 AM PDT “There’s Nothing Holdin’ Us Back” from strippin’ down Shawn Mendes‘ birthday to one thing and one thing only: his hottest shots! From towel pics to smokin’ snaps (literally, smoking 🚬), it’s no shocker the Grammy-nominee shows off what he’s workin’ […]

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How to target £1m for a child in a Stocks & Shares ISA by 30

How to target £1m for a child in a Stocks & Shares ISA by 30

Image source: Getty Images In the UK, individuals can open a Stocks and Shares ISA from age 18, with an annual allowance of £20,000. Over 13 years — by age 30 — that’s a potential £260,000 in contributions. Even with strong returns, that alone likely won’t reach £1m. In fact, it would require 20% annual […]

Bitcoin Technical Analysis – Fed and Trump gave the market a boost

Bitcoin Technical Analysis – Fed and Trump gave the market a boost

Fundamental Overview Much like the stock market, Bitcoin found support this week from the dovish comments from Fed members. Fed’s Williams was the first opening the door for a cut in September which marked the bottom in many risk assets. That was followed by Fed’s Daly and Fed’s Kashkari who cited the NFP report and […]

The efficacy and safety of inhaled peptide YKYY017 for COVID-19 patients with mild illness: a phase 2 randomized controlled trial

The efficacy and safety of inhaled peptide YKYY017 for COVID-19 patients with mild illness: a phase 2 randomized controlled trial

This randomized, placebo-controlled phase 2 trial assessed the efficacy and safety of YKYY017, an inhaled aerosolized membrane fusion inhibitor, for the treatment of COVID-19. Most enrolled patients had mild COVID-19 disease. The primary outcome of the phase 2 trial was not met. Although inhaled 20 mg YKYY017 demonstrated a signal for higher viral load reduction on […]

Study finds adverse childhood experiences increase children’s risk of exposure to smoke

Study finds adverse childhood experiences increase children’s risk of exposure to smoke

Credit: Pixabay/CC0 Public Domain A new study reveals a troubling connection between adverse childhood experiences and children’s exposure to tobacco smoke in their homes. The study was led by University of Cincinnati researcher Ashley Merianos, who specializes in tobacco use and its effects. The research, published in Child Protection and Practice, highlights that in the […]