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A quinolone N-oxide antibiotic selectively targets Neisseria gonorrhoeae via its toxin–antitoxin system

A quinolone N-oxide antibiotic selectively targets Neisseria gonorrhoeae via its toxin–antitoxin system

Growth of bacterial strains Neisseria strains were cultured in PPM medium (15 g l−1 proteose pepton, 1 g l−1 soluble starch, 5 g l−1 NaCl, 4 g l−1 KH2PO4, 1 g l−1 K2HPO4, pH 7.5) for liquid culture and on GC plates (BD Difco, GC Medium Base), both supplemented with 1% IsoVitale vitamin mix (100 g l−1 glucose, 10 g l−1 glutamine, 26 g l−1 l-cysteine, 100 mg l−1 carboxylase, 250 mg l−1 NAD, 500 µl l−1 […]

Christina Fulton Says Val Kilmer Was Very Generous With Her on ‘Doors’ Set

Christina Fulton Says Val Kilmer Was Very Generous With Her on ‘Doors’ Set

Christina Fulton I Love You, Val … Generous With His Time on ‘The Doors’ Set Published April 2, 2025 3:56 PM PDT Play video content TMZ.com Christina Fulton is another one of Val Kilmer’s heartbroken former costars … speaking to us about her favorite memories with him. TMZ caught up with Christina outside the courthouse […]

Crypto takes another bath on Trump tariff tade war

Crypto takes another bath on Trump tariff tade war

Now is not the time for a backgrounder on the institutional adoption of crypto, such as Bitcoin, and how this has brought it in closer correlation with more established risk assets. But … its been sold off alongside the moves in stocks, risk FX and more: ETH is under US$1800 as I post. If you […]

An ACE2-Fc decoy produced in glycoengineered plants neutralizes ancestral and newly emerging SARS-CoV-2 variants and demonstrates therapeutic efficacy in hamsters

An ACE2-Fc decoy produced in glycoengineered plants neutralizes ancestral and newly emerging SARS-CoV-2 variants and demonstrates therapeutic efficacy in hamsters

Ethics declaration and biosafety statements The animal experiment was approved by the Institutional Animal Welfare Committee of the Institut de Recerca i Tecnologia Agroalimentàries (CEEA-IRTA, registration number CEEA 365/2023) and by the Ethical Commission of Animal Experimentation of the Autonomous Government of Catalonia (registration number CEA-OH/12069/1) and conducted by certified staff. Experiments with SARS-CoV-2 were […]

Algorithm helps predict outcomes after total knee arthroplasty

Algorithm helps predict outcomes after total knee arthroplasty

Credit: Pixabay/CC0 Public Domain A research team led by David C. Ayers, MD, has identified important factors in total knee replacement that predict outcomes five years after surgery. The manuscript is currently available online and will be published in the Journal of Arthroplasty. It identifies the following key predictors for patient outcomes five years after […]

Cash transferring giant Zelle shuts down mobile app

Cash transferring giant Zelle shuts down mobile app

Bank of America Chairman and CEO Brian Moynihan talks anticipating policy and regulation changes, the economic future in 2025, bank growth, rate trajectory and investment into artificial intelligence. Payment processing platform Zelle shut down its standalone application Tuesday, redirecting users to banks and credit unions offering its services instead. When attempting to sign in to […]

Poll: Who Will Win The AL Central?

Poll: Who Will Win The AL Central?

Opening Day has finally arrived, and teams all around the league are gearing up for another pennant chase in hopes of being crowned this year’s World Series champion. Of course, there’s still another seven months to go before someone raises the Commissioner’s Trophy. Until the playoffs begin, teams will be focused on a smaller goal: […]

Bucks shoot highest single-match field goal percentage since 1998

Bucks shoot highest single-match field goal percentage since 1998

Before Tuesday’s game, Giannis Antetokounmpo told his Milwaukee teammates that they had to fight for their lives if they wanted to contend for the NBA title this year, and they responded by shooting the highest-single game percentage by any time during this current century.  This means that during their 133-123 victory over the Suns, the […]