NFL odds, Vegas traces, picks, spreads, recreation predictions: Mannequin eyeing 49ers, Packers in Week 5, 2024

Cowboys vs. Steelers is likely one of the uncommon non-conference NFL rivalries due to their postseason historical past. Their three Tremendous Bowl conferences are the commonest within the recreation’s historical past. The 2 will conflict on Sunday Night time Soccer in Week 5, and Pittsburgh is a 2.5-point residence favourite within the NFL odds after opening as a 1.5-point underdog. Steelers vs. Cowboys might be a Tremendous Bowl 59 preview, as might the Monday Night time Soccer recreation of Chiefs vs. Saints, which has Kansas Metropolis favored by 5 in line with the newest Week 5 NFL spreads.

There are a number of different intriguing Week 5 NFL matchups exterior of primetime on the Week 5 NFL schedule. Ravens vs. Bengals (+2.5) kicks off at 1 p.m. ET on Sunday, as does Bills vs. Texans (+1), which has one of many slimmest NFL betting traces of the week. Within the late afternoon, a pair of 2-2 divisional rivals will sq. off in Broncos vs. Raiders (+2.5). All the Week 5 NFL lines are listed under, and SportsLine’s advanced computer model has all the NFL betting advice and NFL predictions you need to make the best Week 5 NFL picks now.

The mannequin, which simulates each NFL recreation 10,000 occasions, is up nicely over $7,000 for $100 gamers on A-rated NFL picks since its inception. The mannequin enters Week 5 of the 2024 NFL season on an unbelievable 188-131 run on top-rated NFL picks that dates again to the 2017 season. It is usually on a 42-23 roll on A-rated NFL picks since Week 7 of the 2022 NFL season.

The mannequin additionally ranked within the prime 10 on NFLPickWatch 4 of the previous six years on straight-up NFL picks and beat greater than 94% of CBS Sports activities Soccer Decide’em gamers 4 occasions throughout that span. Anybody who has adopted it’s approach up.

Now, it has turned its consideration to the newest Week 5 NFL odds and NFL betting traces on the spread, money line, and over-under, and locked in picks for each NFL matchup. Head here to see every pick.

Prime Week 5 NFL predictions

We are able to let you know one of many mannequin’s strongest Week 5 NFL picks is that the 49ers (-7.5, 49.5) cowl the unfold versus the Cardinals. San Francisco is near full power after getting again Deebo Samuel and George Kittle final week, and it was obvious in its end result versus New England. The 49ers prevailed 30-13, with the 17-point victory being their largest since Week 13 of final season. The Niners had a season-high of 431 yards and compelled three turnovers, whereas Arizona is coming off a 28-point residence loss to Washington, which ties for its fifth-biggest residence defeat over the past 35 years.

The 49ers have defeated the Cardinals in 4 straight conferences, however they have not simply scraped by as they’ve blown out their divisional rivals as every of these wins got here by not less than 16 factors. The Cardinals enter Week 5 with back-to-back ATS defeats, and their straight-up document of 9-29 since 2022 is the worst within the NFL. The mannequin expects San Francisco’s domination of Arizona to proceed, with the Niners profitable by greater than two touchdowns and protecting as 7.5-point favorites nicely over 60% of the time. See which other teams to pick here.

One other one among its Week 5 NFL betting predictions: the Packers (-3.5, 48) cowl on the street versus the Rams. Inexperienced Bay is coming off a defeat to Minnesota wherein Jordan Love made his return and was clearly rusty early on. The Packers fell right into a 28-0 gap, however they then outscored the Vikings 29-3 over the past 35 minutes of the sport. Love set career-highs in each passing yards (389) and touchdowns (4) forward of a matchup with a Rams protection which ranks thirty first in each factors allowed and yards allowed.

Los Angeles simply allowed Caleb Williams to have his finest professional recreation, with career-highs in each completion proportion and passer score, in a loss to the Bears. L.A. might additionally solely muster one landing on offense as that aspect of the ball has obvious weaknesses. The Rams have the No. 28 speeding offense and are nonetheless lacking WRs Cooper Kupp and Puka Nacua within the passing recreation. Love ought to be rather more constant one other week faraway from his harm, which has the mannequin predicting Inexperienced Bay (-3.5) covers nicely over 50% of the time. The mannequin additionally says the Over (47.5) hits in over 50% of simulations. See which other teams to pick here.

The way to make Week 5 NFL picks

The mannequin has additionally made the decision on who wins and covers in each different recreation on the Week 5 NFL schedule and simply revealed three groups that win outright not less than 70% of the time, doubtlessly providing you with an enormous payday. You can only get every pick for every game at SportsLine.

So what NFL picks are you able to make with confidence, and which three must-see groups must you lock in now? Take a look at the newest NFL odds under, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned well over $7,000, and discover out.

Week 5 NFL betting odds, traces, spreads

Get Week 5 NFL picks at SportsLine

Thursday, Oct. 3

Buccaneers at Falcons (-1.5, 43.5)

Sunday, Oct. 6

Jets vs. Vikings — in London (-2.5, 40.5)

Panthers at Bears (-3.5, 42)

Ravens at Bengals (+2.5, 50.5)

Payments at Texans (+1, 47)

Colts at Jaguars (-3, 46.5)

Dolphins at Patriots (-1, 35.5)

Browns at Commanders (-3.5, 44.5)

Raiders at Broncos (-2.5, 36.5)

Cardinals at 49ers (-7.5, 49.5)

Packers at Rams (+3.5, 48)

Giants at Seahawks (-6, 43.5)

Cowboys at Steelers (-2.5, 43)

Monday, Oct. 7

Saints at Chiefs (-5, 42.5)